Hou Yi

Name

姓名

YiHou/侯毅

Gender

性别

Male/男

College

学院

Collegeof Life Science and Technology

生命科学与技术学院

Highestdegree

最高学历

Ph.D.

博士研究生

ProfessionalTitle

职称

AssociatedProfessor/副教授

Discipline/Major

专业

PhysicalChemistry/物理化学

ResearchArea/Direction

招生研究方向

PhysicalChemistry; Polymer Physical Chemistry; Biomedicine

物理化学；高分子物理化学；生物医学

OfficePhone

办公电话

CellPhone

手机号码

Email

邮箱

houyi@mail.buct.edu.cn

ResearchTopics（nomore than 100 words）研究方向

1.Constructinghypersensitive molecular imaging nanoprobes for tumor diagnosis;

2.Establishing the“multitarget-triggered logic” nanoprobes fordisclosing the correlation between tumor-associatedmicroenvironments and tumor behaviors;

3.Exploiting thenanoparticle-protein corona to improve tumor targeting ofnanomedicine.

EducationBackground 教育背景

• 2004– 2009Department of Chemical Physics, University of Science andTechnology of China, PhD in Physical Chemistry of Polymers,advisor: Professor Guangzhao Zhang.

• 2000–2004Department of Chemical Physics, University of Science andTechnology of China, BScinChemical Physics

WorkExperience 工作经历

• 08/2019– Present: AssociatedProfessor, Collegeof Life Science and Technology, Beijing University of ChemicalTechnology.

• 07/2011–08/2019: AssociatedProfessor, Instituteof Chemistry, Chinese Academy of Sciences.

• 05/2010– 05/2011:Postdoctoral Fellow, Departmentof Chemistry, University of Toronto.

Publications(nomore than 10 representative publications) 发表文章

1. PeisenZhang, YiHou*,Jianfeng Zeng, Yingying Li, Zihua Wang, Ran Zhu, Tiancong Ma,and Mingyuan Gao* "Coordinatively Unsaturated Fe³⁺Based Activable Probes for Enhanced MRI and Therapy of Tumors"Angew.Chem. Int. Ed.2019,58,11088-11096.

2. XiaodanSun^‡,Peisen Zhang^‡,YiHou*,Yingying Li, Xiaodan Huang, Zihua Wang, Lihong Jing*, andMingyuan Gao* "pH-Sensitive Ratiometric Fluorescent Probefor Evaluation of Tumor Treatments" Chem.Eng. Process.2019,142,107551.

3. TiancongMa^‡,Peisen Zhang^‡,YiHou*,Haoran Ning, Zihua Wang, Jiayi Huang, and Mingyuan Gao "‘Smart’Nanoprobes for Visualization of Tumor Microenvironment"Adv.Health. Mater. 2018,7,1800391.

4. TiancongMa^‡,Yi Hou^‡,JianfengZeng^‡,Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, andMingyuan Gao* "Dual-RatiometricTarget-Triggered Fluorescent Probe for Simultaneous QuantitativeVisualization of Tumor Microenvironment Proteases and pH invivo"J.Am. Chem. Soc. 2018,140, 211-218.(co-firstauthor)

5. JiayiHuang, YiHou*,Tiancong Ma, Peisen Zhang, Yingying Li, Chunyan Liu, BoyuanZhang, Shanshan Qiu, Jianfeng Zeng, and Mingyuan Gao*"ANovel Histochemical Staining Approach for Rare-Earth BasedNanoprobes"Adv.Therap. 2018,1, 1800005.

6. ZhenyuGao^‡,Yi Hou^‡,JianfengZeng, Lei Chen, Chunyan Liu, Wensheng Yang*, and Mingyuan Gao*"Tumor Microenvironment-Triggered Aggregation ofAnti-Phagocytosis ^99mTc-LabelledFe₃O₄Nanoprobes for Enhanced Tumor Imaging in Vivo" Adv.Mater. 2017,29, 1701095.(co-firstauthor)

7. YiHou, JinZhou, Zhenyu Gao, Xiaoyu Sun, Chunyan Liu, Dihua Shangguan,Wensheng Yang, and Mingyuan Gao* "Protease-ActivatedRatiometric Fluorescent Probe for pH Mapping of MalignantTumors" ACSNano 2015,9, 3199-3205.

8. XiaoyuSun, Bingru Wang, Ivan M. Kempson, Chunyan Liu, YiHou*,Miangyuan Gao*"Restructuring and Remodeling of NaREF₄Nanocrystalsby Electron Irradiation" Small2014,10, 4711-4717.

9. YiHou,Ruirui Qiao, Fang Fang, Xuxia Wang, Chengyan Dong, Kan Liu,Chunyan Liu, Zhaofei Liu, Hao Lei*, Fan Wang, Mingyuan Gao*"NaGdF₄ Nanoparticle-BasedMolecular Probes for Magnetic Resonance Imaging ofIntraperitoneal Tumor Xenografts In Vivo" ACSNano 2013,7, 330-338.

10. ChunyanLiu, Zhenyu Gao, Jianfeng Zeng, YiHou*,Fang Fang, Yilin Li, RuiruiQiao, Lin Shen, Hao Lei, WenshengYang, Mingyuan Gao* "Magnetic/Upconversion FluorescentNaGdF₄:Yb,ErNanoparticle-based Dual-modal Molecular Probes for invivoTumor Imaging" ACSNano 2013,7, 7227-7240.