北京化工大学硕博留学生导师简介
Name 姓名 | Yu changyuan | Gender 性别 | Male | Photo 照片 | |
College 学院 | |||||
Highest degree 最高学历 | Doctor degree | Professional Title 职称 | Professor | ||
Discipline/Major 专业 | Life Science | ||||
Research Area/Direction 招生研究方向 | Biomedical | ||||
邮箱 | yucy@buct.edu.cn | ||||
Research Topics(no more than 100 words)研究方向 | tumor immunology ,new drug development, multi-omics and molecular diagnostics. | ||||
1. Tumor Immunology 2. Molecular Diagnostics 3. Bioinformatics | |||||
Education Background 教育背景 | |||||
Xiangya Medical College, Central South University,Ph. D | |||||
Work Experience 工作经历 | |||||
2005.3-present College of Life Science and Technology, Beijing University of ChemicalTechnology, Professor 2002.9-2005.2 Institute of Basic Theory for Chinese MedicineChina Academy of Chinese Medical Sciences ,Postdoc Associate 1992.10-1999.8 Institute of Materia Medica,Jiuzhitang Pharmaceutical Co. Ltd Director, Senior Engineer 1984.8-1992.9 Xinjiang Malan Base Army Hospital Xinjiang, Military Medical Officer | |||||
Publications(no more than 10 representative publications) 发表文章 | |||||
(1) Polymorphism analysis and supertype definition of swine leukocyte antigen class I molecules in three-way crossbred (Landrace, Duroc, and Yorkshire) pigs: implications for the vaccine development of African swine fever virus. Sci China Life Sci. 2020;63(10):1604-1607. (2) A high-throughput single cell-based antibody discovery approach against the full-length SARS-CoV-2 spike protein suggests a lack of neutralizing antibodies targeting the highly conserved S2 domain. Brief Bioinform. 2022;23(3). (3) Design and synthesis of cinnamic acid triptolide ester derivatives as potent antitumor agents and their biological evaluation. Bioorg Med Chem Lett. 2022;67:128760. (4) Specific subsets of urothelial bladder carcinoma infiltrating T cells associated with poor prognosis. Sci Rep. 2023;13(1):12801. (5) Increasing the glucose metabolism enhances the bioelectricity generation in microbial fuel cells. Acta Biochim Biophys Sin (Shanghai). 2022;54(10):1566-1567. (6) Over-expressing NadA quinolinate synthase in Escherichia coli enhances the bioelectrochemistry in microbial fuel cells. Biol Open. 2023;12(3). (7) High affinity monoclonal antibody targeting Siglec-15 for cancer immunotherapy. J Clin Transl Res. 2021;7(6):739-749. (8) Imidazole modified Pt(iv) prodrug-loaded multi-stage pH responsive nanoparticles to overcome cisplatin resistance. Chem Commun (Camb). 2020;56(76):11271-11274. (9) MnO(2) Decorated Metal-Organic Framework-Based Hydrogel Relieving Tumor Hypoxia for Enhanced Photodynamic Therapy. Macromol Rapid Commun. 2023;44(19):e2300268. (10) Apurinic/apyrimidinic endonuclease triggered doxorubicin-releasing DNA nanoprism for target therapy. Cell Cycle. 2022;21(24):2627-2634. |